How does a Virus cause Cancer?

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Navin
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How does a Virus cause Cancer?

Post by Navin » Fri Jul 28, 2006 7:14 am

Cancer occurs when there is a mutation in the DNA of a cell leading to oncogenes or even loss of function of tumor supressive genes.

However, I am unclear how a virus may cause cancer.

I think that it has got to do something with the lysogenic cycles of certain viruses because it is only during that cycle where the virus' genome is integrated into that of the host cell.

Am i close to the answer or am i totally straying from it?
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Post by victor » Fri Jul 28, 2006 10:42 am

remember how a virus' genetic material get intergrated with host's DNA?? that's how the mutation on host occur to be oncogenic..
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Post by Navin » Fri Jul 28, 2006 11:17 am

is it a form of frameshift mutation?
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Post by victor » Fri Jul 28, 2006 11:46 am

Yup...insertion of viral genetic material cause a frameshift mutation in host cell's DNA.. :mrgreen:
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Post by tjaymac » Mon Aug 07, 2006 9:50 am

Any idea where i can find one of those cancer causing viruses?

I am doing this project on eradication of tumor cells by use of red light, so i need to initiate cancer in mice...
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Post by sdekivit » Mon Aug 07, 2006 11:20 am

human papilloma virus (HPV) is a famous cancer-causing virus.

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Post by victor » Mon Aug 07, 2006 11:41 am

there're Papilomavirus, Hepadnavirus, Herpesvirus, Poxvirus and Retrovirus. (well, those're what I can remember..:lol: )
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Thanks folks

Post by tjaymac » Mon Aug 07, 2006 2:11 pm

Thanks fellas for the info...like it had skipped me...i was looking for some much more complex stuff/ways to initiate the cancer.....Plis do visit my forum "Project X" under Cell biology
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