hexokinase in liver and muscle

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kabuto
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hexokinase in liver and muscle

Post by kabuto » Wed Apr 12, 2006 2:36 pm

what is the difference between hexokinase in liver and muscle?

i think it is related to aerobic and anaerobic respiration.

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Enzyme
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Post by Enzyme » Wed Apr 12, 2006 5:29 pm

Hello kabuto! ;)

The hexokinase phosphorilates hexoses in general (as its name shows), but has more affinity for glucose than for fructose.

In muscle there is hexokinase, but in liver there is an isoenzyme of that called glycokinase (which has different kynetic properties and is specific only for glucose). We can consider hexokinase and glycokinase as 'the same' enzyme, but they differe in many kynetic characteristics (e.g. Km, etc).

I don't know if your doubt is referring to this... :?
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kabuto
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Post by kabuto » Thu Apr 13, 2006 7:59 am

We can consider hexokinase and glycokinase as 'the same' enzyme, but they differe in many kynetic characteristics (e.g. Km, etc).


so, what is the consequences?

anything to do with respiration or metabolisme?

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