epps?

[neworder]

epps?

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Post by neworder » Fri Mar 17, 2006 2:52 pm

Hi, I'm a neurobiology student trying to understand end-plate potentials. I'm trying to solve a problem that asks about how the EPP would change in different circumstances. I understand that if you add an acetylcholinesterase inhibitor, you would get a bigger, longer EPP. But what if you add just acetylcholine? I found two conflicting source, where one says the EPP would increase and one says it would stay the same. I'm not sure the reasoning behind it in any case.

I wonder if you guys can help me out...thanks!
Jen

[MrMistery]

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Post by MrMistery » Fri Mar 17, 2006 6:45 pm

Is an end plate potential a potential that takes place on a motor fiber when stimulated by Acetylcholine? I am having a translation problem. If it is so, then yes, adding extra acetylcholine will produce an extended muscle contraction

[neworder]

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Post by neworder » Fri Mar 17, 2006 11:16 pm

Hi, I'm sorry for not defining it better. Your definition was right and thanks for responding to my question. Do you, or does anyone know, what the relationship between the epp and the membrane capacitance is?
I have this awful problem set and I can't find the answers anywhere!
Thanks anyone who can help!

[MrMistery]

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Post by MrMistery » Sat Mar 18, 2006 8:55 pm

membrane capacitance? I might, if you tell me what that is..

[neworder]

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Post by neworder » Sun Mar 19, 2006 4:15 pm

Hmm...I think capacitance is the amount of charge stored. So the bigger the membrane the more capacitance. I guess that means that if you suddenly increase the capacitance the more charge needed, so you decrease the amplitude of the end-plate potential.
Thanks!
Jen