MOSAIC!!

Genetics as it applies to evolution, molecular biology, and medical aspects.

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nugget
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MOSAIC!!

Post by nugget » Wed Mar 15, 2006 7:23 am

Hello all,
i have been reading about Klinefelters syndrome a whole lot and yet i havent seemed to figure out what the difference between mosaic and non-mosaic is, if anybody knows ... please :D
Cheers,

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Poison
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Post by Poison » Wed Mar 15, 2006 5:21 pm

If someone knows, please tell me what does "mosaic" and non-mosaic" refers to...
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sham
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Post by sham » Thu Mar 16, 2006 2:40 am

Female has two X chromosomes. But one X chromosome was inactivated during embryonic development. Which X chromosome inactivated is random in each cell of a female. Therefore each female is a mosaic of genetically different tissue patches (depends on which X is inactivated). For example, female haterozygous carrier for red-green colour blindness will have patches of retinal cells with defective colour vision interspersed among patches of normal vision. In Klinefelter syndrome (XXY), the male is also a mosaic because of the inactivation of one X chromosome. Normal male is a non-mosaic.
Sham

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Post by MrMistery » Thu Mar 16, 2006 7:48 pm

Oh yes, now i remember reading about this is a 9th grade book. But i though it was just a metaphore, i didn't know it is an actual genetics term...
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Poison
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Post by Poison » Fri Mar 17, 2006 7:12 pm

Thanks.
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Post by sdekivit » Fri Mar 17, 2006 7:55 pm

it is a genetics term. There is a big difference between mosaics and chimeras when describing chromosomal abnormalities.

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nugget
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Post by nugget » Sun Mar 19, 2006 2:18 am

Thank you very much, it cleared up my confusion, all the other explanations i was finding didnt make sense as yours did. :) :D

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