Discussion of all aspects of cellular structure, physiology and communication.
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First it is determined by number,kind..sequence of amino acids that make the polypeptide chain. Polypeptide chain is folding..hydrogen bonds form between C=O and H (pleated sheet,alpha helix)..also disulfide bonds form between aminoacids that contain sulfur(cysteine). Conformation is important because function of protein depends of its shape(just look simplified key-lock model)
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