up and down regulation

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marinola
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up and down regulation

Post by marinola » Wed Feb 01, 2006 7:30 pm

I have read the definition of down-regulation, but I don´t get it.
Could anyone give a try?
Thanks in advanced

sdekivit
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Post by sdekivit » Thu Feb 02, 2006 11:37 am

for example: the downregulation of membraneproteins

--> when a ligan binds, the signal produced by the liogand must be stopped. one way is receptor downregulation, in which the receptor is internalized and degraded in the lysosome.

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Dr.Stein
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Post by Dr.Stein » Fri Feb 03, 2006 8:15 am

I love signaling pathways :)
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