Estradiol Inhibition in the Follicular Phase

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galpinj
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Estradiol Inhibition in the Follicular Phase

Post by galpinj » Fri Sep 09, 2016 9:11 am

Hi everyone,

So I initially memorized some facts about the uterine and ovarian cycle, but I have always had difficulty accepting one aspect of the cycle. In the follicular phase the concentration of estradiol (estrogen) is very low, and this inhibits both the release of LH and FSH by the anterior pituitary as well as GnRH by the hypothalamus. This doesn't make any sense to me though, as I feel that the follicle needs the follicle STIMULATING hormone in the early stages to develop and thus produce more estrogen. How do the early follicles mature when all the necessary hormones are being inhibited from the very beginning?

Thank you everyone for your insights in advance.
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