Penicillin Production

About microscopic forms of life, including Bacteria, Archea, protozoans, algae and fungi. Topics relating to viruses, viroids and prions also belong here.

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Shaayadh
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Penicillin Production

Post by Shaayadh » Fri Oct 23, 2015 12:26 pm

What are the conditions for production of Penicillin?

bioscience56
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Post by bioscience56 » Wed Oct 28, 2015 2:22 am

3-8 C
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Asiaferret
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Post by Asiaferret » Sat Dec 26, 2015 8:58 am

Penicillin G is produced by Penicillium Chrysogenum that does aerobic respiration. Spores of these fungus are first inoculated into a fed-batch fermenter with the appropriate medium and left to run. 40 to 48 hours later, nutrients will be added at a constant interval, equal amount of waste will be removed at regular intervals. The products are harvested after 7 days. The cells will be filtered from other products (sometimes by a rotary vacuum filter). The antibiotic will then be filtered and extracted by acetic acid and sodium acetate at low temperature. Then purification and packaging is done. I may be wrong. Check some relevant sources to see if I left out anything.

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