Mutation

Genetics as it applies to evolution, molecular biology, and medical aspects.

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hanna92
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Mutation

Post by hanna92 » Thu Oct 16, 2014 4:44 pm

Hi. I really need help to understand this question.

A patient has been brought to you with symptoms suggesting the human gene which is equivalent to the Drosophila TCF gene is not being transcribed in some of the cells in which it is normally transcribed. Your hypothesis is that the patient has a mutation in the human equivalent of the Drosophila DSH gene, and that this mutation alters the protein so that it does not function. This lack of function is the reason for the lack of transcription of the TCF gene. What test or tests would you do to determine if the patient has such a mutation? What results would you expect from your test if your hypothesis is correct? Briefly explain your reasoning.

Please, thank you.

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