Debate and discussion of any biological questions not pertaining to a particular topic.
3 posts • Page 1 of 1
So I think I have proof of concept for my finger which are long bones but there are some differences between finger bones and long bones.
I need you to validate that the finger on the right hand is longer. I have some before pictures but it's a lot easier to see the gains side by side. I only clamped the right index finger and not the left. The right index finger is about 1/4" longer. The increase is not due to any genetic effect or to altered growth during puberty which I can prove if you decide to take it seriously.
The length increase is due an increase in bone length and not due to enlargement of the synovial cavity. I can compare individual bones between one finger than another(although the difference is much harder to see).
My fingers do have osteophytes and the bone change in length in size is not typical of normal finger growth. It is for instance much wider than normal.
So I need someone to validate that the finger length increase is legit. I can provide any other documentation that me be needed.
The idea is that this increase can be applied to the long bones just more force/pressure may be needed.
I am not quite sure why it works but the method is based on Lengthening of Mouse Hindlimbs by Joint Loading by Ping Zhang/Hiroki Yokota. However, I had to use much more load than is present in the study(fairly intense clamping). Possible reasons could be related to hydrostatic pressure, changes in gene expression in stem cells resulting in differentiation, osteoclast degradation enabling interstitial growth, or gene signaling from the articular cartilage/synovial joint. When the articular cartilage is loaded it results in the release of water upon deformation and perhaps cartilagenous signals trigger processes in the epiphysis.