Osmolarity calculation

Discussion of all aspects of cellular structure, physiology and communication.

Moderators: Leonid, amiradm, BioTeam

Post Reply
Terence
Garter
Garter
Posts: 2
Joined: Thu Dec 22, 2005 9:26 pm

Osmolarity calculation

Post by Terence » Thu Dec 22, 2005 9:40 pm

I want to calculate what the sodium ion concentration is in blood after someone's blood glucose had increased, by say 5 mM. For the sake of argument treat glucose as cell impermeant. It is known that blood sodium really does correlatate negativly with blood glucose. The assumption being that the increased osmotic pressure draws water from the extreacellular > intracellular compartments, diluting the permeant ions e.g. sodium, which is most abundent. But I can't find a formula for estimating this theoretically.

The starting values I have are:

Na+ 142 mOsm/L
Total osmotic pressure in plasma: 5443 mOsm/L
Both ISF and ICF are 5423 mOsm/L
Plasma volume aprx. 3 litres

Thank-you in advance for any clues :-)

Terence

Post Reply

Who is online

Users browsing this forum: Google [Bot] and 2 guests