farnesyl-transferase

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f_moosavi2004
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farnesyl-transferase

Post by f_moosavi2004 » Sun Dec 18, 2005 10:38 am

hello
what means "farnesyl-transferase"
thanks

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MrMistery
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Post by MrMistery » Sun Dec 18, 2005 5:49 pm

An enzyme. It catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Inhibitors are used to treat certain kinds of cancer
By the way, it is spelled farnesyltransferase. In the future, check google before you post here if you want to get your answer faster.
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter

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