drugs and heart rate
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- countyclare
- Garter
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- Joined: Mon Dec 12, 2005 5:04 am
drugs and heart rate
Does anyone know of a good journal article that talks about the mechanisms and subsequent effects of ethanol and caffeine (separately) on heart rate? I know ethanol decreases heart rate and caffeine increases, but how is what I am unsure of. Thanks in advance to anyone who can help me!!! 

- chicoguardian
- Coral
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try this site, I think think it should have plentful enough info that you will need... http://kidshealth.org/teen/drug_alcohol ... drugs.html
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- MrMistery
- Inland Taipan
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Don't knwo about alcohol's effect on heart cells, but i do know that caffeine activated something called the Rynoadin receptor, a protein located in the endoplasmic reticulum. This is actually a calcium channel that transports it via facilitated diffusion into the cytoplasm. Another level where caffeine function is that it inhibits the production of an enzyme named phosphodiesterase that results in cAMP not being recycled.
About alcohol, all i know about influences on the cardiovascular system is that it determines a peripherical vasodilatation
About alcohol, all i know about influences on the cardiovascular system is that it determines a peripherical vasodilatation
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter
MrMistery wrote:Don't knwo about alcohol's effect on heart cells, but i do know that caffeine activated something called the Rynoadin receptor, a protein located in the endoplasmic reticulum. This is actually a calcium channel that transports it via facilitated diffusion into the cytoplasm. Another level where caffeine function is that it inhibits the production of an enzyme named phosphodiesterase that results in cAMP not being recycled.
About alcohol, all i know about influences on the cardiovascular system is that it determines a peripherical vasodilatation
those receptors are called ryanodine receptors and are involved in the so called calcium-induced calcium-release.
cAMP is also very important in the cardiac contraction, since cAMP binds to the If-channels in the sinoatrial node holding them open for a longer period and thus an increased heart rate.
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