URGENT HELP PLEASE: tgf-b GENE REGULATION

Debate and discussion of any biological questions not pertaining to a particular topic.

Moderators: honeev, Leonid, amiradm, BioTeam

Post Reply
sallywiski
Garter
Garter
Posts: 3
Joined: Sat Dec 10, 2005 8:07 pm

URGENT HELP PLEASE: tgf-b GENE REGULATION

Post by sallywiski » Sat Dec 10, 2005 8:15 pm

Hi,
a simple question...I seem to have found contradicting evidence that TGF-B downregulates Cyclin A and thrombosporin-1, is it true?

I know that it upregulates type 1 collagen and CTGF but I stand unclear about cyclin A and TSP-1.
I would appreciate your help.
Thanks
Sally

sdekivit
King Cobra
King Cobra
Posts: 586
Joined: Sat Jul 30, 2005 7:16 pm
Location: holland
Contact:

Post by sdekivit » Sun Dec 11, 2005 10:49 am

TGF-B does downregulate cyclin A by increasing gene expression of p21, a cdk activating kinase inhibitor

Post Reply

Who is online

Users browsing this forum: No registered users and 2 guests