Enzymes and tertiary structure

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Death Adder
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Enzymes and tertiary structure

Post by Starlight189 » Thu Dec 01, 2005 10:48 pm

Ok so enzymes are proteins with a tertiary structure...but what is the importance of this structure to the functioning of the enzyme? :?

Thanks :)
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King Cobra
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Post by sdekivit » Fri Dec 02, 2005 7:27 am

you know what tertiary structure is? --> its spacial conformation.

you know that enzymes are highly specific ?

--> what would happen with the activity of an enzyme when it's conformation is altered, and thus it's binding site for its ligand is different?

It wouldn't bind to it's ligand anymore and so the enzyme is inactive due to an altered tertiary structure.

--> plays a major role in signal transductionpathays, for example by phosphorylating proteins so they get a conformational change and become active or inactive. All changes in tertiary structure :D

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