Neurosecretory Cells

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zenith_beth
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Neurosecretory Cells

Post by zenith_beth » Tue Nov 29, 2005 7:36 pm

"Information", in the form of hormones, passes from the hypothalamus to the pituitary gland via neurosecretory cells. How are these neurosecretory cells adapted for their role in secretion? :?:
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MrMistery
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Post by MrMistery » Tue Nov 29, 2005 8:01 pm

Do you mean the cells that produce ADH and oxitocin? Well, they have big cellular bodies with a vey well developed endoplasmic reticulum and Golji apparatus.
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Post by zenith_beth » Wed Nov 30, 2005 7:28 pm

Yes, those are the ones I was referring to. The ER and Golgi are important in the production of the hormones... but is there anything else which has to do with secretion?
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Post by MrMistery » Wed Nov 30, 2005 8:05 pm

Do you know what secretion actually means on a cellular level? It basically means releaseasing of secretion vesicle formed in the TGN. Check the role of the golgi apparatus and you will see that one of the main function is creation of secretion vesicles.
So yes, Well developed RER and Gogli apparatus and a large number of mitocondria are adaptations to secretion. You can not divide secretion from production in this case.

Another adaptation is the production of it's own proteins, called neurophisines, that are nothing more than a special class of MAP(microtubule associated proteins). They transport the hormones at a speed of 3 mm/day from the cellular body along the axon to the terminal side.
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Post by zenith_beth » Mon Dec 05, 2005 5:18 pm

Thanks for explaining it!! :)
wizzie :-)

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