DNA Gyrase vs. DNA Helicase

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jayson
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DNA Gyrase vs. DNA Helicase

Post by jayson » Tue Nov 29, 2005 2:10 am

What is the difference between the two ? (not structurelly (sp?), but by function)

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Post by sdekivit » Tue Nov 29, 2005 8:58 pm

DNA gyrase produces DNA supercoiling and DNA helicase unwinds DNA

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Post by jayson » Tue Nov 29, 2005 8:58 pm

Doesn't Gyrase also relive the tension from the DNA strand.

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Post by Jennifer » Wed Nov 30, 2005 1:37 am

DNA helicase unwinds the double helix by disrupting the hydrogen bonds of the base pairs of nucleotides. DNA gyrase relieves the tension from the unwinding of the double helix by cutting the strand, and reannealing it once the tension has been released.
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Post by sdekivit » Wed Nov 30, 2005 3:32 pm

NOOOOOOO!!!!!! DNA gyrase = DNA topoisomerase II and produces negative supercoils

--> DNA topoisomerase I relaxes these negative supercoils.

DNA helicase pulls the DNA strands away from each other for transcription and is completely different from producing/relaxing supercoils

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