mRNA

Discussion of all aspects of biological molecules, biochemical processes and laboratory procedures in the field.

Moderators: honeev, Leonid, amiradm, BioTeam

Post Reply
User avatar
Jennifer
Garter
Garter
Posts: 20
Joined: Mon Nov 28, 2005 10:16 pm
Location: Canada! :)

mRNA

Post by Jennifer » Mon Nov 28, 2005 10:42 pm

Can anyone tell me the destiny of mRNA after it has been used to code for protein? I know that the nucleotides are reused, but I have to be really specific!
Any help would be awesome! :)
~*Jennifer*~

User avatar
jayson
Garter
Garter
Posts: 27
Joined: Sun Nov 27, 2005 4:55 am

Post by jayson » Tue Nov 29, 2005 2:08 am

I think they get digested by the enzymes in the cytoplasm. That is why they add the poly-a-tail to the 3' end, to prevent the digestion of the codons.

sdekivit
King Cobra
King Cobra
Posts: 586
Joined: Sat Jul 30, 2005 7:16 pm
Location: holland
Contact:

Re: mRNA

Post by sdekivit » Tue Nov 29, 2005 9:00 pm

Jennifer wrote:Can anyone tell me the destiny of mRNA after it has been used to code for protein? I know that the nucleotides are reused, but I have to be really specific!
Any help would be awesome! :)


i think the mRNA is ubiquitinated and degraded in the proteasome.

User avatar
Jennifer
Garter
Garter
Posts: 20
Joined: Mon Nov 28, 2005 10:16 pm
Location: Canada! :)

Post by Jennifer » Wed Nov 30, 2005 1:35 am

Thanks! :D
~*Jennifer*~

cool A-level student
Death Adder
Death Adder
Posts: 61
Joined: Thu Nov 24, 2005 11:19 am

Post by cool A-level student » Wed Nov 30, 2005 2:15 pm

mRNA or messenger RNA is a single strand of copied DNA which ends up at the ribosomes where it is changed into amino acids and thus proteins using the instructions from the mRNA.

mRNA is made so that its not all "messy" in the cell with all the DNA going everywhere, so mRNA is copied to give a small part of instructions to where it is needed without being messy
neat huh?

User avatar
MrMistery
Inland Taipan
Inland Taipan
Posts: 6832
Joined: Thu Mar 03, 2005 10:18 pm
Location: Romania(small and unimportant country)
Contact:

Post by MrMistery » Wed Nov 30, 2005 8:58 pm

I don't remember how it works actually, but the same mRNA molecule codes for the same protein many times before it is degraded by enzimes. What i don't remember is how the cell decides if it needs more protein or not. probably some receptor that stimulates the recycling of cAMP for protease synthesis or something...
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter

nick4106
Garter
Garter
Posts: 3
Joined: Thu Dec 01, 2005 12:37 am

Post by nick4106 » Thu Dec 01, 2005 12:42 am

It is degraded by proteasomes in the cell. They degrade used and misfolded proteins into 7-9aa strands.

Post Reply

Who is online

Users browsing this forum: No registered users and 4 guests