Yeast resistance

About microscopic forms of life, including Bacteria, Archea, protozoans, algae and fungi. Topics relating to viruses, viroids and prions also belong here.

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Avery
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Yeast resistance

Post by Avery » Sun Nov 27, 2005 5:49 pm

Any ideas as to why yeast would be naturally resistant to streptomycin? I think it has something to do with yeast (which is a fungi) having to be able to grow in antibiotic conditons, but I'm not sure. If anyone knows of an article about this let me know.

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MrMistery
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Post by MrMistery » Sun Nov 27, 2005 5:51 pm

Evolution?
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canalon
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Post by canalon » Sun Nov 27, 2005 9:59 pm

More likely, yeast being an eucaryotes shouldn't be sensitive to an antobiotic targeting the ribosome. Antibiotics being selected to poison procaryotes and not eucaryotes. Other wise they would just be called poison :wink:
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victor
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Post by victor » Mon Nov 28, 2005 1:21 pm

One of the antibiotics is the cuinolon family which targetting the DNA and do something for the DNA transcription...is this kind of antibiotic still have no effect with the yeast??
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canalon
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Post by canalon » Mon Nov 28, 2005 2:45 pm

Quinolones are no exception. Antibiotics that are targetting a system shared by the bacteria and the host must differentiate between them at the dose used to be usefull. Otherwise whatwould be the point? To die healthy? :wink:
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GreenDog
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Post by GreenDog » Tue Nov 29, 2005 12:33 pm

Streptomycin targets 70S bacterial ribosomes, Yeast have 80S eukaryotic ribosomes, their structure is different. Why would Streptomycin target them at all?

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