The P-53 gene

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123Herpatology
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The P-53 gene

Post by 123Herpatology » Sun Nov 06, 2005 5:54 am

The p-53 gene (or guardian angel gene) controls proliferating cancer cells from getting too large. Is this correct, i know it has something to do with controlling cancerous cells. Does anyone know how it does this? And does the P-53 gene help with all types of cancer, or is there a selection of cancer types that it focuses on.
wisdom=the anti-venom for failure

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Dr.Stein
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Post by Dr.Stein » Sun Nov 06, 2005 9:46 am

Well check THIS out, this is a nice article of p53 gene, maybe your question will be answered :)
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MrMistery
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Post by MrMistery » Sun Nov 06, 2005 5:27 pm

Nice to see you again Dr. Stein
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter

sdekivit
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Post by sdekivit » Sun Nov 06, 2005 9:10 pm

check 'molecular biology of the cell' by alberts et al. :D

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Post by tursiops » Tue Nov 08, 2005 10:06 pm

when a DNA damage occours, some signals from ATM go towards p53 that inhibits or induces other proteins/enzimes to arrest cell cycle and permits DNA repair or, if the damage is big, p53 induces apoptosis.
Non-functional p53s are one of the reason of cancer.
I hope that these lecture are helpful for you:
p53 pathway and p53

123Herpatology
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yes!

Post by 123Herpatology » Wed Nov 09, 2005 4:52 am

Thanks for all the links, tons of info and good cites for my bibliography!
wisdom=the anti-venom for failure

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