What is VNTR's and RFLP?

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starlet7000
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What is VNTR's and RFLP?

Post by starlet7000 » Sun Oct 30, 2005 12:11 am

What is VNTR's and RFLP? Also what are they used for in genetic technology?

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Morris
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Post by Morris » Sun Oct 30, 2005 8:51 am

VNTR means: Variable number of tandem repeats; is a polimorfism where alleles of a chromosome are differents for number of repetitions.
RLFP involve restriction sites; a mutation can alter a restriction site or insertion of a deletion of a DNA fragment can generate restriction fragment of variable lenght; these fragments are called RFLP.

sdekivit
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Post by sdekivit » Sun Oct 30, 2005 10:46 am

VNTR's are used for example for person-identification or identification of a biological child of a mother.

RFLP (not RLFP) are used for disease investigation --> sickle cell anemia and disease of Duchenne are for example examined based on a RFLP
Last edited by sdekivit on Sun Oct 30, 2005 10:48 am, edited 1 time in total.

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Morris
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Post by Morris » Sun Oct 30, 2005 10:48 am

Sorry it's RFLP, i wrote wrong....

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vntrs and rflp

Post by lara » Wed Nov 09, 2005 11:11 am

RFLP stands for restriction fragment length polymorphism.when restrictases cut strands the length of the fragments produced are characteristic of the strand.SNPs(single nucleotide polymorphism)and other mutations can change the length as they alter the cuttin' sites for restrictases.rflp can be used for genetic diagnosis of diseases .

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