rbc survival ?

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siya
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Post by siya » Thu Nov 03, 2005 5:39 am

well the fact that rbcs lack nuclei increase their efficiency.the abcence of nucleus makes the rbcs biconcave and the help them carry more oxygen.
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Post by vinaya » Thu Nov 03, 2005 12:14 pm

:shock: :shock: :shock: 8) 8) 8) really i had no idea
thanks a lot
btw, how does the biconcave shape help in transpot of O2 :?:

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Poison
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Post by Poison » Thu Nov 03, 2005 12:27 pm

biconcave shape makes it easy to travel through cappilaries.
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Post by zenith_beth » Mon Nov 07, 2005 8:17 pm

It baffles me too coz the nucleus is responsible for producing proteins and the rbc is full of Hb which is a protein. If it does not produce this protein during its lifetime ie. it has a certain amount from the beginning and retains it till it dies, then i see no point for having a nucleus in a rbc. So the question should really be whether the rbc produce the Hb themselves?
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Post by canalon » Mon Nov 07, 2005 8:19 pm

zenith_beth wrote:It baffles me too coz the nucleus is responsible for producing proteins and the rbc is full of Hb which is a protein. If it does not produce this protein during its lifetime ie. it has a certain amount from the beginning and retains it till it dies, then i see no point for having a nucleus in a rbc. So the question should really be whether the rbc produce the Hb themselves?


They do before fully maturating. They lose their nucleus in the later stage of maturation and are released then in the blood stream.
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Post by zenith_beth » Thu Nov 10, 2005 6:20 pm

Ok, so then if they don't produce any Hb during their "no-nucleus" stage, then there is no need for a nucleus. If anything it would interfere with the red blood cell's function because having no nucleus means that the rbc can pack more Hb and therefore do its job more efficiently!
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Post by biostudent84 » Thu Nov 10, 2005 6:27 pm

Poison wrote:How can it use O2 without any metabolic activity? :)


Actually, RBC's are able to make energy. They are able to carry out the first state of Glycosis to make 2 net ATP's, as this stage is carried out in the cytoplasm, not in the mitochondria.

And if memory serves, blood cells only remain in the blood stream for 90 days...

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Post by zenith_beth » Fri Nov 11, 2005 9:40 am

vinaya wrote::shock: :shock: :shock: 8) 8) 8) really i had no idea
thanks a lot
btw, how does the biconcave shape help in transpot of O2 :?:

The biconcave shape helps with more efficient transport of O2 because this way O2 has to diffuse a shorter distance to "reach" the Hb in the rbc, then if the rbc was spherical!!
wizzie :-)

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Post by Bio-Hazard » Tue Nov 29, 2005 4:57 pm

What signals for the erasal of the RBCs to the liver/spleen?

They run around the body for 120 days and then get disposed, but what signals the body to say, "Alright, you're all damaged up and ready to kick the bucket, time to go to the oven!"

Is there a biochemical that is released? Is there a lock and key system where if the RBC become so damaged that it doesn't fit thus it becomes destroyed? What is the biomechanical and biochemical system behind this?

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Poison
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Post by Poison » Tue Nov 29, 2005 5:04 pm

biostudent84 wrote:
Poison wrote:How can it use O2 without any metabolic activity? :)


Actually, RBC's are able to make energy. They are able to carry out the first state of Glycosis to make 2 net ATP's, as this stage is carried out in the cytoplasm, not in the mitochondria.


I meant aerobic respiration, not anaerobic respiration.
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