What does allosteric mean?

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onyx
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What does allosteric mean?

Post by onyx » Wed Oct 26, 2005 10:21 pm

What is meant by and allosteric protein? Why are G-protein linked receptors described as allosteric, while tyrosine kinase receptors are not?

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canalon
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Post by canalon » Thu Oct 27, 2005 12:08 am

allosteric describe a regulation of an enzyme activity by anoter ligand that binds on another site than the substrate of the enzyme.
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Morris
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Post by Morris » Fri Oct 28, 2005 6:01 pm

Allosteric means that when a lignad binds to a site for example in a protein that have four subunits as emoglobine, it makes easier the binding of others ligands to the others sites of the protein, because it causes a structural modification of other sites.... I hope I'm not wrong and that you can understand my explanation.. ;)

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