Upstream and downstream region

Genetics as it applies to evolution, molecular biology, and medical aspects.

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starlet7000
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Upstream and downstream region

Post by starlet7000 » Sun Oct 23, 2005 11:49 am

What is the difference between upstream region and down stream region? Also I'm confuse with terms lagging strands and promoter region.

sdekivit
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Post by sdekivit » Sun Oct 23, 2005 4:30 pm

upstream is near the 5'-side and downstream is near the 3'-side.

now the difference between lagging strand and promoter region. These are two completely different things.

--> there is a leading strand and a lagging strand during DNA replication. The leading strand is the strand that can be completely synthesized by DNA-polymerase --> hence it's longer. The lagging strand cant be synthesized completely but has to be done with Okazaki-fragments (replication from 3' --> 5' can't be done thus a loop in the DNA is needed leading to Okazaki-fragments). The lagging strand is thus shorter.

A promoter region plays a role in gene expression and is a part of an operon. This a particular DNA-sequence leading to products that can be regulated.

starlet7000
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Post by starlet7000 » Mon Oct 24, 2005 11:52 am

Thanks :D

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