new dna form

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lara
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new dna form

Post by lara » Tue Oct 04, 2005 9:51 am

read that p-form of dna(in vitro) has the phosphates facin' inwards,any idea???

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MrMistery
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Post by MrMistery » Tue Oct 04, 2005 7:21 pm

I have never heard of the p-form of DNA. I know B-form(natural), A-form and Z-form but P-form? Sorry, can't help...
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Post by hurly » Wed Oct 05, 2005 3:59 pm

Care to explain what all of these X-forms are...? :?

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Post by MrMistery » Thu Oct 06, 2005 7:28 pm

In a transversal section:
A-form: there is a central empty space, sugars and phosphates are at the margns and the nitrogen bases are towards the center
B-form: nitrogen bases are towards the center and the phosphates and sugars towards the margins(outside) of the macromolecule. The centre is filled with the nitrogen bases, there is no space
Z-form: appears as the compenents were distributed all around the matrix of the helix, with no specific domains. Actually the sugars and phosphates are towards the centre and the N bases on the outside.
Is this enough info or do you need more? cause i am lazy and do not want to write things without a point..
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hurly
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Post by hurly » Thu Oct 06, 2005 7:47 pm

Thanks for taking time explaining it to me :D

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Post by ak537 » Fri Oct 07, 2005 12:01 pm

can you please elaborate p-form of DNA then I might be able to say something :)

lara
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p-form

Post by lara » Fri Oct 07, 2005 4:50 pm

allright.p-form is found in vitro,on artificial xtension.this is all i know.can u make out sumthin' of it?? :lol:

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Chris4
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Re: p-form

Post by Chris4 » Sat Oct 08, 2005 12:19 am

lara wrote:allright.p-form is found in vitro,on artificial xtension.this is all i know.can u make out sumthin' of it?? :lol:


DNA undergoes a stretching phase transition at a force of 65 pN; above this force, DNA is thought to take the form that Linus Pauling originally hypothesized, with the phosphates in the middle and bases splayed outward. This proposed structure for overstretched DNA has been called "P-form DNA," in honor of Pauling.

From: http://en.wikipedia.org/wiki/Mechanical ... ies_of_DNA
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Post by ak537 » Sat Oct 08, 2005 12:11 pm

thanks for such a nice explation about P form.

lara
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new form of dna

Post by lara » Sat Oct 15, 2005 10:39 am

what's the idea of bases splaying outwards?can we still call it dna??

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MrMistery
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Post by MrMistery » Sat Oct 15, 2005 6:16 pm

Sure we can, just another type of DNA
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lara
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new form of dna

Post by lara » Mon Oct 17, 2005 11:21 am

what about the H-bonds between the bases ,then??

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