FAD and NAD+

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vantan
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FAD and NAD+

Post by vantan » Sat Sep 10, 2005 11:24 am

hello :)

at the moment i am studying for the exam: biochemistry and i don`t understand one thing! actually, i can not find good explanation: what is difference between NAD+ and FAD - i know how they look, where is their place in reactions, even biosynthesis, but why sometimes NAD and sometimes FAD?

i think i`ve missed the point :?

thanx

vantan

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Post by victor » Sat Sep 10, 2005 11:52 am

From what I know, both NAD+ and FAD+ are electron acceptors. they accept e- that are generated within glycolysis and Krebs cycle..then these e- will be sent outside inner mitochondrion membrane and get them in again through ATP sintase to form ATP.
These reaction happen in krista mitochondria
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Post by MrMistery » Tue Sep 13, 2005 7:46 pm

I think this has been said 20 times already but i will say it for the 21th time. The difference is in how much energy it releases. NADH realeases 3 ATP, FADH2 only 2 ATP
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Post by victor » Wed Sep 14, 2005 11:10 am

I think this kind of question is the most popular one in this forum.. :lol:
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Post by sdekivit » Wed Sep 14, 2005 2:59 pm

MrMistery wrote:I think this has been said 20 times already but i will say it for the 21th time. The difference is in how much energy it releases. NADH realeases 3 ATP, FADH2 only 2 ATP


but it's 'indirect' correct ;) Looking only at the molecule, the difference is where it releases it's electrons to the electrontransport chain. They both release 2 electrons.

From this point there follows a difference in energy that can be produced due to the generation of a different proton gradient.

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Post by MrMistery » Wed Sep 14, 2005 8:06 pm

Yeah, yeah... We know sdekivit. it's been discussed only 50 times. :D :D :D
Seriosly.. To all the new members, try to search the forum before asking something. it is quite big and we have quite a lot of things here
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Post by b_d_41501 » Thu Sep 15, 2005 5:55 pm

3 ATP FADH2 per 4 electrons and 2 ATP NADPH per 4 electrons according to my molecular book. By the way, just had my first Molecular Biology of the Cell exam and I got a 90%!!!
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Post by MrMistery » Thu Sep 15, 2005 7:37 pm

Hmm.. I knew them the other way around but i may be wrong, since there cellular respiration is not my thing. But NADPH? That is only in photosynthesis from what i know...
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Post by b_d_41501 » Thu Sep 15, 2005 8:32 pm

My bad guys, you couldn't tell from my post I made a 90%. It IS the other way around and I meant to say NADH, not NADPH. Sorry guys. :oops:
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Post by vantan » Fri Sep 16, 2005 4:34 pm

i believe you didn`t understand my question really - i DO know that NADH realeases 3 ATP, FADH2 only 2 ATP!!!

but, i was reading more and found out what i wanted to know - during reduction, NAD and NADP move 2H as ions: one H with 2electrons and H as proton, without electrons; and FAD (and FMN) move two atoms of H - it means 2H, but each has one electron.
and FAD is tighter connected with its enzyme.

uhhh...

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Post by b_d_41501 » Sun Sep 18, 2005 7:58 pm

Sorry we couldn't be of more help, perhaps you should be more specific in you questions in the future. :D
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Post by nastou16 » Tue Sep 20, 2005 11:24 am

i am proffesor of biology and i need this item for students in high school

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