Bacteriophage Question

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cytochromeP
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I guess NOT

Post by cytochromeP » Fri Sep 16, 2005 9:05 pm

Hi,
Lets say one somehow managed to get a bacteriophage inside a human cell.
In order for a bacteriophage (any virus for that matter) to "infect" a human cell it must be able to replicate its DNA inside the human cell.
DNA replication involves many stages - intiation, elongation and termination. Each of these require specific activator proteins and most importantly some enzymes to do the job.
Inside an E.Coli, DNA Polymerase I and III do the job of DNA replication. A bacteriophage exploits this host bacterium machinery to get its DNA replicated. But the human DNA replicase wont be able to replicate the phage replicon.
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Seda
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Post by Seda » Fri Sep 16, 2005 11:28 pm

Hi everyone!!!
Yes, bacteriphages are viruses that infect only bacteria. Bacteriophages also called as phages are bacterial viruses and they cannot infect human also any eukaryotic cells. Their mechanisms were different as mentioned before.

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