Confusion about Missense Mutation

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mekovi
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Confusion about Missense Mutation

Post by mekovi » Sat Jul 02, 2011 6:25 am

Textbook says that it may or may not alter the Amino acid sequence of a protein, while the definition on this site is "A form of point mutation resulting in a codon that codes for a different amino acid, and thus, causes the synthesis of a protein with an altered amino acid sequence during translation."

Help please :)

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JackBean
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Post by JackBean » Sat Jul 02, 2011 8:07 am

missense mutation IMHO means, that the sense of sequenced is changed, thus it should be the second definition.

The first one is probably about point mutations in general.
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.

magicsiew
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Post by magicsiew » Sat Jul 02, 2011 12:06 pm

Yes, agree with JackBean, missense mutation will alter the amino acid. If may not alter the amino acid, we call that silent mutation.

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