Why do antibiotics cause cell death with lipofectamine

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mcwhat
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Why do antibiotics cause cell death with lipofectamine

Post by mcwhat » Fri Jun 17, 2011 3:45 pm

I understand the presence of antibiotics in media will lead to cell death when you use lipofectamine, but I have not been able to find a mechanism. I have heard that it is related to an increase in cell membrane permeability that leads to antibiotics getting into the cells causing cell death . But I have not seen any papers that support this? Do other methods of enhancing cell membrane permeability also lead to cell death in the presence of antibiotics?

Thank you,
Mike

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