help please! Genetics question probability of offspring bein

Genetics as it applies to evolution, molecular biology, and medical aspects.

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help please! Genetics question probability of offspring bein

Post by jacobamark99 » Wed Jun 08, 2011 1:52 am

This question is driving me crazy

So, I saw this question in the textbook example but I'm unsure of how they did it
Carrier frequency for a rare autosomal recessive aa condition is 1/10
what is the probability two phenotypically normal individuals will produce an phenotypically normal offspring...

parents can be AA or Aa probability of them being Aa is 1/10 ...but what about them being AA
would it be 9/10*9/10 * 3/4 normal if both parents were AA???

thanks in advance

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Post by JackBean » Wed Jun 08, 2011 6:16 am

you probably have to calculate the rate of homozygotes from p2 + 2pq + q2

Cis or trans? That's what matters.

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