Aberrations in replication of e.coli?

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Aberrations in replication of e.coli?

Post by LunaMoon7 » Mon May 23, 2011 6:50 pm

I've looked everywhere, and can't find anything to help me out on this problem. Any help would be appreciated.

Suggest the possible cause of each of the following aberrations during replication in E. coli:
1. Accumulation of Okazaki fragments.
2. The presence of RNA in newly synthesized DNA strand.
3. Many mismatched base pairs.
4. DNA replication does not initiate.

Thanks for your help!

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Inland Taipan
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Post by JackBean » Tue May 24, 2011 8:02 am

1. what joins Okazaki fragments?
2. how are the primers replaced?
3. how are the mismatches repaired?
4. how does the DNA replication initiate?

If you can answer all these questions (and I guess you should be able to do so), then you know the answers ;)

Cis or trans? That's what matters.

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