Nomenclature/designation question

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Nomenclature/designation question

Post by geneticsquest » Thu Jul 22, 2010 5:43 pm

For a loss-of-function nonsense mutation (C to T) in an SRY gene which would be the correct designation for the mutant allele?
A) sry^m (^=superscript)
B) sry^gln
C) SRY*Gln2Ter
D) SRY*(triangle)6fs

*I've ruled out C and D because D would be for deletion mutation and C is just wrong, but I am struggling to chose between A and B....any help please??

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Inland Taipan
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Post by JackBean » Thu Jul 22, 2010 6:32 pm

B IMHO means change into Gln, A is probably just "some" mutation. I would go for D

Cis or trans? That's what matters.

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