A simple problem

Genetics as it applies to evolution, molecular biology, and medical aspects.

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biostud
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A simple problem

Post by biostud » Fri Jun 25, 2010 3:05 pm

Well, we know that during DNA replication there is 1 mistake per 10^9 bases per generation. Well lets suppose we have a gene that contains 10^3 bases. In how many generations there will be one mutation? I think in 10^6 generations! Am i correct? :?:
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mith
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Post by mith » Tue Jun 29, 2010 7:20 pm

those are probabilities fyi, so it's not 1 mistake per 10^9, it's on average 1 mistake per 10^9.
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hashemyemen
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Post by hashemyemen » Thu Jul 01, 2010 3:38 pm

simply, all those mistakes are then repaired.
Almost 1 mistake per 10,000,000 is taking place while DNA replication according to the book of Brooker ( Principles of Genetics ).

Check it out :D
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JackBean
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Post by JackBean » Sat Jul 03, 2010 1:04 am

hashem, hashem, you're talking, well, stupid things again...
Definitely not all the mistakes are repeaired (what about evolution?), but the repair systems increase the efficiency by factor of 100 (with Pol's proof-reading of 100 as well)
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.
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