Discussion of all aspects of biological molecules, biochemical processes and laboratory procedures in the field.
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- Joined: Tue Apr 20, 2010 10:25 am
Why are the amino acids near the n and c terminus of proteins difficult to resolve by x-ray crystallography.
- Inland Taipan
- Posts: 5694
- Joined: Mon Sep 14, 2009 7:12 pm
because the ends are usually at the surface of the protein and are flexible and thus "invisible" for X-ray. It's similar like whit some loops, which are disordered until the substrate is bound
Cis or trans? That's what matters.
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