Transcription unit

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simpleton
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Transcription unit

Post by simpleton » Thu Apr 22, 2010 3:45 pm

Hey guys, can I confirm that transcription unit includes only the 5' untranslated portion, 3' untranslated protion, the active gene sequence? And that it DOES NOT consists of the enhancer?

Secondly, for hormon peptide which does not participate directly in DNA replication; do we still consider them as an co-effector? :?:


Many thanks in advance. :)

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JackBean
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Post by JackBean » Thu Apr 22, 2010 7:02 pm

if is the enhancer located upstream from the translation start, then it's not in the transcript. But I think, there can be some enhancer binding sites, which are located also downstream
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.

simpleton
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Post by simpleton » Fri Apr 23, 2010 9:17 am

yeah, i agree that the location of enhancer is not defined. it can be anywhere. i'm just afraid my prof will give us this question for MCQ. and if enhancer was to be in the option; i got no idea to pick it or not.

thanks jackbean :)

Orome
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Post by Orome » Fri Apr 23, 2010 11:31 am

It`s just not possible to give a Yes/No answer. I think most enhancers lie upstream of 5' UTR but there are also enhancers that lie within intronic regions (http://www.mbi.ufl.edu/~hnick/intronic%20enhancer.htm). Your prof should know this ;) .

Greets
Orome

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