Receptor-mediated endocytosis

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klapausius
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Receptor-mediated endocytosis

Post by klapausius » Fri Apr 16, 2010 1:34 pm

need help wif regard to the question below..
Which of the following stages of receptor mediated endocytosis would not be significantly affected in an environment of pH5 ?

(a) binding of the ligand to the receptor on the plasma membrane
(b) budding of plasma membrane
(c) uncoating of transport vesicles
(d) fusion of transport vesicles with early endosomes

my guess is (d)
but im not sure if its correct

kolean
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Post by kolean » Sat Apr 17, 2010 6:14 pm

I would guess (d) too, as early endosomes are acidic in their environment, and thus the proteins needed for fusion of the transport vesicle would already be affected by a pH5 environment already.

klapausius
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Post by klapausius » Sun Apr 18, 2010 7:21 am

did a check on the early endosome like u said it is of a lower pH
thanx!

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