PCR to screen for diseases

Genetics as it applies to evolution, molecular biology, and medical aspects.

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JackBean
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Post by JackBean » Wed Apr 21, 2010 10:09 am

you don't have to sequence it
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.

Orome
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Post by Orome » Fri Apr 23, 2010 11:51 am

Hey JackBean,
in Diagnostics Multiplex PCR is a standard method. See http://en.wikipedia.org/wiki/Multiplex-PCR for further information.
For example Duchenne/Becker-Muscledystrophy can be detected with this technique.
Another interesting technique is MAPH-analysis which requires PCR and probe hybridization (http://www.dmd.nl/DMD_MAPH.html).

Greets
Orome

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JackBean
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Post by JackBean » Fri Apr 23, 2010 12:31 pm

did I say something else?
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.

Orome
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Post by Orome » Fri Apr 23, 2010 12:41 pm

no, i just wanted to provide some more specific information for the community :)

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