Trisomy Help

Genetics as it applies to evolution, molecular biology, and medical aspects.

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LinuxPoser
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Trisomy Help

Post by LinuxPoser » Thu Feb 25, 2010 1:27 am

A homozygous recessive mutant was crossed to trisomics of two different chromosomes. A testcross of the trisomy F1 to the recessive homozygote gave 42 wild- type and 38 mutant progeny for chromosome 5, and 56 wild-type and 12 mutant progeny for chromosome 6. On which chromosome do you think the gene was located? Why?

I was wondering if someone could explain the concepts of this to me. Went looking in my book and it didn't explain it too well, and I wasn't able to find any good literature on the web.

I assume it has something to do with the ratios explaining which would be more likely. I assume its chromosome 6 since the trisomy over-rode the genetic appearance of the mutant gene. Any help?

bitopandas
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Post by bitopandas » Fri Feb 26, 2010 6:29 am

My first doubt in your question is , can Trisomics replicate. Because in this case there cannot be a division of chromosome number into half, then how will the gamete formation on the trisomics take place??

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