protein folding

Discussion of all aspects of cellular structure, physiology and communication.

Moderators: honeev, Leonid, amiradm, BioTeam

Post Reply
ryanbarnhill
Garter
Garter
Posts: 5
Joined: Wed Nov 18, 2009 3:45 pm

protein folding

Post by ryanbarnhill » Wed Feb 24, 2010 10:49 pm

i'm having trouble understanding exactly how chaperones help proteins fold. BiP particularly can anyone recommend a link?

AndrewPhD
Garter
Garter
Posts: 7
Joined: Wed Feb 24, 2010 6:26 pm

Post by AndrewPhD » Wed Feb 24, 2010 11:47 pm

The chaperonin creates a hydrophobic environment for the denatured protein to be seperated from the factors that caused it to become denatured. But the chaperonin doesnt actually renature the protein itself.

User avatar
JackBean
Inland Taipan
Inland Taipan
Posts: 5694
Joined: Mon Sep 14, 2009 7:12 pm

Post by JackBean » Thu Feb 25, 2010 7:11 am

again, don't forget the GroEL-GroES complex. It uses bunch of ATP, so this one is for sure active process
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.

ryanbarnhill
Garter
Garter
Posts: 5
Joined: Wed Nov 18, 2009 3:45 pm

Re: protein folding

Post by ryanbarnhill » Thu Feb 25, 2010 6:16 pm

thanks guys.

Post Reply

Who is online

Users browsing this forum: No registered users and 1 guest