Classification RNAs

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raghavagps
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Classification RNAs

Post by raghavagps » Sat Jan 23, 2010 7:18 am

Dear Friends
Their are different types of RNAs (coding, non-coding) like mRNA, t-RNA, miRNA, r-RNA. Its not clear to me how cell decide the type of RNA, I mean why certain RNA string is treated miRNA and other is treated as t-RNA. Form me all are RNA sequence. Is their any method/algorithm which can classify type of RNA, I mean if I give RNA string can this method tell type of RNA. Your help will be highly apprecuiated.

With Regards

Raghava

G P S Raghava (FASc FNASc), Scientist & Head Bioinformatics Centre,
Institute of Microbial Technology, Chandigarh, India.
Last edited by JackBean on Sat Jan 23, 2010 11:14 am, edited 1 time in total.
Reason: link removed

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mith
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Post by mith » Sat Jan 23, 2010 9:19 pm

I don't understand the question, are you saying you can't distinguish RNA in a cell or on a database?
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JackBean
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Post by JackBean » Sat Jan 23, 2010 10:19 pm

IMHO, they are trying to distinguish different RNA types by sequence to do some program or database.
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.

kolean
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Post by kolean » Sun Jan 24, 2010 9:14 pm

I got this one by googling ncRNA databases:
http://biobases.ibch.poznan.pl/ncRNA/
from there you can also utilize BLAST for ncRNA.

You have to realize that RNA has a functional structure too. It is not just a string of nucleotides all strung together without shape. These functional structures are conserved thru most of the model organisms that are being studied and experimented on, and documented. That is where the databases come in. Yes, you can put in a string and they can predict what RNA it could be based on what they already know, and there are databases like miRBase Targets that can even show you if your ncRNA has a target.

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