Direction of transcription

Genetics as it applies to evolution, molecular biology, and medical aspects.

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abiran
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Direction of transcription

Post by abiran » Sat Nov 28, 2009 2:16 am

Im getting really confused What do you mean by the RNA pioymerase 'reads" the template strand in 5'-3' strand.

http://en.wikipedia.org/wiki/File:Simpl ... ation1.svg

in this picture isnt the strand moving in 3'to5' direction?so what do you mean by reading in 5" to 3" direction?
like i don tget the expression "READ'.
Thank you
PLzz help
thnx agian

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JackBean
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Post by JackBean » Sat Nov 28, 2009 12:58 pm

Where did you get it? That is the direction of new strand synthesis
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.

kolean
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Post by kolean » Sat Nov 28, 2009 3:41 pm

The RNA polymerase "transverses" the template/noncoding strand in the 3' - 5' direction, but it "reads" the template/noncoding strand in the 5' - 3' direction (forward looking at it). Like the RNA polymerase is 'facing' towards the 5' end and the 3' end is behind you as it 'reads' the DNA. This will then produce the 5' - 3' mRNA, which will be the same as the coding template (hence the name) that is in the 5' - 3' direction.

abiran
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Post by abiran » Sun Nov 29, 2009 10:41 pm

Thank you so much that made things a lot cleareer..

tempust
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Post by tempust » Thu Dec 17, 2009 1:52 am

It actually moves in the 5' -> 3' direction. The new complementary strand is synthesized in the 3' -> 5' direction.
Don't worry, I was ridiculously confused about it at first. You should get a fellow student or your teacher to draw out on the board the whole process, labeling everything. I don''t know, it helped for me.

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