Tripeptide in organic solvent

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PimpleMan
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Tripeptide in organic solvent

Post by PimpleMan » Sun Nov 08, 2009 6:30 am

I have two non-polar amino acids and I am trying to determine which would be most likely to be soluble in an hydrophobic organic solvent. The third option is either proline or glycine. Which would be the most hydrophobic? From my text book and the internet they both appear to have the ability to form hydrophobic tripeptides.

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JackBean
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Post by JackBean » Sun Nov 08, 2009 7:03 am

1) and will you tell us, which amino acids you have?
2) althrough the side chain may be nonpolar, the NH2-C(alpha)-COOH is not
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.

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Re: Tripeptide in organic solvent

Post by PimpleMan » Sun Nov 08, 2009 8:03 am

I going to say that phenylalanine, alanine, glycine would be the most likely to be soluble. Thanks for your advice.

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JackBean
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Post by JackBean » Sun Nov 08, 2009 9:02 am

You're welcome :lol:

Why not L or I?

I would be so sure about F, there is some trick, when comparing F and Y. Unfortunatelly, I don't remember, what was it :-(
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.

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Re: Tripeptide in organic solvent

Post by PimpleMan » Sun Nov 08, 2009 10:24 am

My assignments are all question which require I draw on knowledge that is not present in my textbook, which makes it fairly confusing at best. Does anyone know a good website for cell bio, or more specifically how I could determine which amino acid sequence would be the most soluble in a (hydrophobic) organic solvent such as benzene? (Or I might have myself, if this has anything to with adding up hydropathy)

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JackBean
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Post by JackBean » Sun Nov 08, 2009 11:19 am

1) do you really think, that you will find better info on inthernet instead of in book? :roll:
2) if you said benzene immediatelly, than it's sure to use as much aromatic AAs (F, Y, W) as possible ;)
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.

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Re:

Post by PimpleMan » Sun Nov 08, 2009 10:11 pm

JackBean wrote:1) do you really think, that you will find better info on inthernet instead of in book? :roll:
2) if you said benzene immediatelly, than it's sure to use as much aromatic AAs (F, Y, W) as possible ;)


I only have introductory organic chemistry knowledge. I'm wondering if Cell Biology requires a bit more than that?

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JackBean
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Post by JackBean » Mon Nov 09, 2009 4:28 am

not really :) Depends, how much you wish to be good and how much are are able to learn at time, when you need it ;)
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.

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