Exonic splicing enhancer

Genetics as it applies to evolution, molecular biology, and medical aspects.

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Cscientist
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Exonic splicing enhancer

Post by Cscientist » Wed May 06, 2009 8:05 am

Hi everybody!
How can I know if an identifyed SNP is present in a exonic splicing enhancer region?
Thank you in advance ;)

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jonmoulton
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Post by jonmoulton » Wed May 06, 2009 3:24 pm

Lay a steric-blocking oligo across the SNP and see if splicing changes.

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Post by Cscientist » Thu May 07, 2009 7:27 am

Thanks! I think I'll try it ;)

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jonmoulton
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Re: Exonic splicing enhancer

Post by jonmoulton » Thu May 07, 2009 4:40 pm

Wonderful. If I can assist with oligo design, let me know.

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