What is A ADAM GENE ??????/????

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CXCR4
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What is A ADAM GENE ??????/????

Post by CXCR4 » Sat May 02, 2009 6:08 pm

Hello to everyone on Biology-online I just wanted to know if some one perhaps know what a ADAM

gene is. I' ve been doing a little studying in the Genetic field but I may have gone a little to in depth.

If you could help or could give an opinion that would help a bunch, Thank you Biology-Online.
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MrMistery
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Post by MrMistery » Sun May 03, 2009 5:44 pm

Well there is an ADAM gene family, they are a family of extracellular metalloproteases that cleave the extracellular portion of membrane proteins. from what I know, there are at least 5 different genes in that family. they are involved (at least) in the first steps in the activation of the Notch Receptor. I remember the ADAM proteases have also been connected with Alzheimer's disease, but not how unfortunately.
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter
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