Activation of myosin?

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Vangeek
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Activation of myosin?

Post by Vangeek » Wed Feb 11, 2009 3:15 am

Could anyone help me to describe the activation of myosin? Is it when ATPase in the myosin head hydrolyzes ATP to ADP and P which provides energy needed to return myosin head to its prestroke high-energy? Or it is when ATP attaches to myosin head and detach the cross bridge? Please help!!!!

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MrMistery
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Post by MrMistery » Wed Feb 11, 2009 4:21 am

it's kind of a weird question, but I would guess that if I had to pick I would say the ATP-bound state is the activated state..
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Vangeek
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Post by Vangeek » Wed Feb 11, 2009 5:10 am

Complete question was this: Every muscle contraction involved the interaction of myosin and actin filaments. This interaction can occur only after myosin has been activated. Describe the activation of myosin. ??? I guess, without both, ATP-bound state that detaches myosin head, or later ATP hydrolysis that sets myosin head into high-energy config for subsequent cross-bridge, interaction between myosin and actin would not be possible??

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