simpleast wya to make animal live longer

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steelcat
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simpleast wya to make animal live longer

Post by steelcat » Thu Oct 23, 2008 9:10 am

what is the simplest way to make animal live longer
1) knock or copy a special genes
2) extend Telomeres
3) Stem Cell
4)Induced Pluripotent Stem Cell:

I think is (1). because (2) there is no much experiment on extend Telomeres
and. (3) (4) is mostly about regrowing a organ.

Adamx
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Post by Adamx » Mon Oct 27, 2008 7:10 am

Well, telomere length can indicate mortality risks. A cell's lifespan integrity depends on this, no?

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mith
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Post by mith » Mon Oct 27, 2008 2:03 pm

The question is simplest, pretty sure 1 is not the simplest.
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jota13
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Post by jota13 » Tue Nov 18, 2008 12:20 pm

I think telomeres have the solution, but it's a cellular solution; I don't know if it would work with associations of cells.

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Chumbawamba
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Post by Chumbawamba » Fri Nov 21, 2008 4:03 am

jota13 wrote:I think telomeres have the solution, but it's a cellular solution; I don't know if it would work with associations of cells.

Right, as there are vital organs which don't replicate cells (brain, muscles usually). So preventing telomere shrinking in these vital organs is pointless.

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MrMistery
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Post by MrMistery » Sat Nov 22, 2008 4:13 am

both muscles and brain cells make cells for their whole lifetime.
The point was that just because you can make an individual cell live longer that does not mean the whole organism will live longer.
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter

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Chumbawamba
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Post by Chumbawamba » Sat Nov 22, 2008 4:38 am

MrMistery wrote:both muscles and brain cells make cells for their whole lifetime.
The point was that just because you can make an individual cell live longer that does not mean the whole organism will live longer.

They do? I always thought they never did. The rate must not be nearly as high as other cells if they do divide.

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Post by MrMistery » Sat Nov 22, 2008 8:44 pm

neurons and adult mucle cells obviously do not divide, but both organs contain stem cells that make new cells through the lifetime of the individual.
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter

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Re: simpleast wya to make animal live longer

Post by misterzed » Wed Dec 17, 2008 3:27 am

There has been some work recently suggesting restriction of calorie intake can increase life expectancy.*

http://www.newscientist.com/article/dn8950-cutting-calories-may-boost-your-lifespan.html

Its also been tested in rats with some interesting results

And in one study the lifespan of yeast has been extended 1000% using the same method.

*Though obviously keeping an animal on the brink of starvation its entire life isn't going to have positive effects on its quality of life, so not exactly something recommendable.

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