sialic acid Question

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erchdvd
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sialic acid Question

Post by erchdvd » Sun Sep 28, 2008 6:22 am

Is there sialic acid in the human body other than the red blood cells? If so could you give me a reference. Thank you.

stopherlogic
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Post by stopherlogic » Sun Sep 28, 2008 8:56 am

Bing Wang, Patricia McVeagh, Peter Petocz and Jennie Brand-Miller (2003) Brain ganglioside and glycoprotein sialic acid in breastfed compared with formula-fed infants. American Society for Clinical Nutrition 78: 1024-9.

As far as I know Sialic acid glycoproteins are found on the surface of various cells but dont quote me on that one.

blcr11
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Post by blcr11 » Sun Sep 28, 2008 12:55 pm

Sialic acid is very common in or on most, if not all, cell membranes.

http://en.wikipedia.org/wiki/Sialic_acid

has a small description with a journal citation. I would think you couldn't help but find something in a standard biochemistry textbook, if it's any good anyway. Look under things like "glycosylation" probably, or possibly under "membrane" or "membrane protein" and things like that. N-neuraminic acid is used within the N- and O-glycosylation pathways and most membrane proteins are also glycosylated to some degree.

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