Overproduction of Cholinesterase

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Overproduction of Cholinesterase

Post by Calculon17 » Thu Sep 04, 2008 3:19 am

We all know about the deadly effects of underproduction of the hormone cholinesterase, but does anyone know of how overproduction of cholinesterase might affect the body? I've searched high and low all over the internet and have not been able to find a single bit of information on this topic.

Any help is appreciated.

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Post by MrMistery » Sun Sep 07, 2008 2:32 am

first of all, cholinesterase is an enzyme not a hormone.
Now, about its overproduction: I don't really think it would make that much of a difference. The fact this(i think), there is already enough cholinesterase in the synaptic cleft to quickly degrade any molecules of acetylcholine that are not attached to the receptor. In an extreme cases, the cholinesterase would simply block the nerve impulse, having similar effects to those of specific inhibitors of the nicotinic and muscarinic acetylcholine receptors.
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter

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