Blood Type

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Maruko
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Blood Type

Post by Maruko » Wed Aug 13, 2008 7:57 pm

Hi,

I don't understand why a person with type A can donate blood to type A or AB ppl, but receive blood from type A or O ppl. Here are my questions:

1) Since type A ppl have antigen A on their red blood cells and anti-B antibodies, when they donate their blood to type AB ppl, wouldn't the anti-B antibodies bind to the B antigen on the AB red blood cells and agglutinate?

2) When a type A person receives blood a type O person, since the type O has anti-A and anti-B antibodies, wouldn't the anti-A antibodies bind to the antigen A on the red blood cell and agglutinate?

3) When we are donating blood, are we donating only the red blood cell (with antigen on it) and no antibodies?

Thanks in advance!

Maruko

MisterATP
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Post by MisterATP » Wed Aug 13, 2008 9:32 pm

I answer just in your first question. I think that will be enough.

Yes, you are right saying that anti-B antibodies bind to B antigen on the AB red blood cells. Say, the donor of type A gives 1 liter a blood. The concentration of anti-B antibodies is pretty small in 1 liter of blood that would be triggered dangerous an agglutination. Clear?

Maruko
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Re: Blood Type

Post by Maruko » Thu Aug 14, 2008 12:58 am

Thank you so much, MisterATP!

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