why nucleus is said to be acid

Discussion of all aspects of biological molecules, biochemical processes and laboratory procedures in the field.

Moderators: honeev, Leonid, amiradm, BioTeam

Post Reply
mageshkov
Garter
Garter
Posts: 1
Joined: Sat Aug 02, 2008 9:58 am

why nucleus is said to be acid

Post by mageshkov » Sat Aug 02, 2008 10:17 am

i do have doubt why nucleus is said to be acidic

MisterATP
Garter
Garter
Posts: 38
Joined: Tue May 13, 2008 7:49 pm

Post by MisterATP » Sat Aug 02, 2008 12:03 pm

It is because of DNA (hence it is acid!)

MikeS
Garter
Garter
Posts: 8
Joined: Fri Aug 15, 2008 10:50 pm

Re: why nucleus is said to be acid

Post by MikeS » Fri Aug 15, 2008 11:58 pm

Good question, I was once puzzled by it too. I always thought DNA contained nitrogenous bases, which are obviously basic. But why are they acidic?

I think the reason is in the phosphate groups. The ATGCs are basic, the (deoxy)ribose are sugers, hence neutral. But the phosphate groups are acidic. This is why when you store DNA, you store them as their salt form, which can be considered the conjugate base of DNA.

A detailed, graphical explanation is available here
My favorite websites:
Publishing Class Notes, Lab Reports, Admission Essays, Papers, Exams online
Reading free books without walking to the library
Searching scientific literature

Post Reply

Who is online

Users browsing this forum: No registered users and 18 guests